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Recent Research


JNJ/PTGX: JNJ2113: Oral dosing faces hurdles of new rival classes in psoriasis & Ulcerative Colitis
The injectable IL23 class has been successful in treating a wide variety of inflammatory conditions such as psoriasis and inflammatory...
Sep 18, 2023


MRK/MRNA: ASCO: vaccine-PD1 similar to historic PD1 alone
New data from MRK/MRNA cancer vaccine at ASCO last week continues to suggest a large underperformance of Keytruda control arm, along with...
Jun 12, 2023


NOVN: NATALEE's Kisqali of Life
As we highlighted in our February 23, 2020 report “Kisqali’s kiss of life“, NOVN's NATALEE trial of Kisqali demonstrated the broadest...
Jun 6, 2023


Still no light from TIGIT trials at ASCO23
While ASCO 2023 does not offer much in updates for the three current lead contenders for anti-TIGIT combinations in non-small cell lung canc
May 28, 2023


mRNA-PD1 cancer vaccine trial control arm may have underperformed
In newly published data from Merck /Moderna’s PD1 + mRNA cancer vaccine trial, efficacy may be flattered by Keytruda alone control arm under
Apr 18, 2023


Little hope in TIGIT trials to date
As expected, TIGIT addition to PD1 failed to beat chemo in second-line patients.
The failure of Merck’s TIGIT+PD1 combo to beat second line
Mar 20, 2023


PFE: ACIP: Prevnar protects against some new but not all old infections
New data from Pfizer’s pneumococcal vaccine reveals inferiority to an important serotype 3 that makes up approximately one third of cases
Feb 23, 2023


PFE pipeline Swim in a big pond if you're 2nd to jump in
We examine in detail, the prospects of five near term Pfizer pipeline assets, slated for the FDA over the next 3 years and find that there a
Dec 21, 2022


BMY/JNJ/BAY: Milvexian moves ahead at ESC
The first factor XIa clinical efficacy for stroke prevention was presented at the European Society of cardiology in Barcelona yesterday...
Aug 28, 2022


Roche: Maintaining Leadership is difficult: nearterm pipeline outlook
We undertake a detailed analysis of seven near term Roche pipeline assets, spanning Roche’s market leading positions in Non-Hodgkin lymphoma to breakthroughs for Duchene muscular dystrophy and find unique assets, but also successful competition
Aug 14, 2022
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